CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Calcium/calmodulin-dependent protein kinase type II subunit delta isoform 2

Enzyme Information

2.7.11.17
Calcium/calmodulin-dependent protein kinase.
based on mapping to UniProt Q13554
ATP + a protein = ADP + a phosphoprotein.
-!- Requires calmodulin. -!- A wide range of proteins can act as acceptor, including vimentin, synapsin, glycogen synthase, myosin light-chains and the microtubule- associated tau protein. -!- Not identical with EC 2.7.11.18 or EC 2.7.11.26. -!- Formerly EC 2.7.1.120 and EC 2.7.1.123.

UniProtKB Entries (1)

Q13554
KCC2B_HUMAN
Homo sapiens
Calcium/calmodulin-dependent protein kinase type II subunit beta

PDB Structure

PDB 3BHH
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal Structure of Human Calcium/Calmodulin-Dependent Protein Kinase IIB Isoform 1 (CAMK2B).
Filippakopoulos, P., Rellos, P., Niesen, F., Burgess, N., Bullock, A., Berridge, G., Pike, A.C.W., Ugochukwu, E., Pilka, E.S., von Delft, F., Arrowsmith, C.H., Edwards, A.M., Weigelt, J., Knapp, S.
To be Published