CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family Chymotrypsinogen A

Enzyme Information

3.4.21.1
Chymotrypsin.
based on mapping to UniProt P00766
Preferential cleavage: Tyr-|-Xaa, Trp-|-Xaa, Phe-|-Xaa, Leu-|-Xaa.
-!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.5 and EC 3.4.4.6.

UniProtKB Entries (2)

P46443
GUAM_HIRNI
Hirudo nipponia
Guamerin
P00767
CTRB_BOVIN
Bos taurus
Chymotrypsinogen B

PDB Structure

PDB 3BG4
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The crystal structure of guamerin in complex with chymotrypsin and the development of an elastase-specific inhibitor.
Kim, H., Chu, T.T.T., Kim, D.Y., Kim, D.R., Nguyen, C.M.T., Choi, J., Lee, J.R., Hahn, M.J., Kim, K.K.
J.Mol.Biol.