CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family SRSF protein kinase 2

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q96SB4
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

Q07955
SRSF1_HUMAN
Homo sapiens
Serine/arginine-rich splicing factor 1

PDB Structure

PDB 3BEG
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
A sliding docking interaction is essential for sequential and processive phosphorylation of an SR protein by SRPK1
Ngo, J.C., Giang, K., Chakrabarti, S., Ma, C.-T., Huynh, N., Hagopian, J., Dorrestein, P.C., Fu, X.-D., Adams, J.A., Ghosh, G.
Mol.Cell