CATH Classification

Domain Context

CATH Clusters

Superfamily 1.10.1200.220
Functional Family

Enzyme Information

2.1.1.278
Indole-3-acetate O-methyltransferase.
based on mapping to UniProt Q9FLN8
S-adenosyl-L-methionine + (indol-3-yl)acetate = S-adenosyl-L-homocysteine + methyl (indol-3-yl)acetate.
-!- The enzyme is found in plants and is important for regulation of the plant hormone (indol-3-yl)acetate. -!- The product, methyl (indol-3-yl)acetate is inactive as hormone. -!- Formerly EC 2.1.1.n10.

UniProtKB Entries (1)

Q9FLN8
IAMT1_ARATH
Arabidopsis thaliana
Indole-3-acetate O-methyltransferase 1

PDB Structure

PDB 3B5I
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural, Biochemical, and Phylogenetic Analyses Suggest That Indole-3-Acetic Acid Methyltransferase Is an Evolutionarily Ancient Member of the SABATH Family.
Zhao, N., Ferrer, J.L., Ross, J., Guan, J., Yang, Y., Pichersky, E., Noel, J.P., Chen, F.
Plant Physiol.