CATH Classification

Domain Context

CATH Clusters

Superfamily Type I PLP-dependent aspartate aminotransferase-like (Major domain)
Functional Family Kynurenine--oxoglutarate transaminase 3

Enzyme Information

2.6.1.7
Kynurenine--oxoglutarate transaminase.
based on mapping to UniProt P47039
L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate.
-!- Also acts on 3-hydroxykynurenine. -!- The product 4-(2-aminophenyl)-2,4-dioxobutanoate is converted into kynurenate by a spontaneous reaction.

UniProtKB Entries (1)

P47039
BNA3_YEAST
Saccharomyces cerevisiae S288C
Probable kynurenine--oxoglutarate transaminase BNA3

PDB Structure

PDB 3B46
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Identification of Formyl Kynurenine Formamidase and Kynurenine Aminotransferase from Saccharomyces cerevisiae Using Crystallographic, Bioinformatic and Biochemical Evidence.
Wogulis, M., Chew, E.R., Donohoue, P.D., Wilson, D.K.
Biochemistry