CATH Classification

Domain Context

CATH Clusters

Superfamily Zn peptidases
Functional Family probable leucine aminopeptidase 2

Enzyme Information

3.4.11.10
Bacterial leucyl aminopeptidase.
based on mapping to UniProt Q01693
Release of an N-terminal amino acid, preferentially leucine, but not glutamic or aspartic acids.
-!- Similar aminopeptidases were isolated from Escherichia coli and Staphylococcus thermophilus. -!- Belongs to peptidase families M17 and M28.

UniProtKB Entries (1)

Q01693
AMPX_VIBPR
Vibrio proteolyticus
Bacterial leucyl aminopeptidase

PDB Structure

PDB 3B35
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Zinc coordination geometry and ligand binding affinity: the structural and kinetic analysis of the second-shell serine 228 residue and the methionine 180 residue of the aminopeptidase from Vibrio proteolyticus.
Ataie, N.J., Hoang, Q.Q., Zahniser, M.P., Tu, Y., Milne, A., Petsko, G.A., Ringe, D.
Biochemistry