CATH Classification

Domain Context

CATH Clusters

Superfamily Zn peptidases
Functional Family probable leucine aminopeptidase 2

Enzyme Information
Bacterial leucyl aminopeptidase.
based on mapping to UniProt Q01693
Release of an N-terminal amino acid, preferentially leucine, but not glutamic or aspartic acids.
-!- Similar aminopeptidases were isolated from Escherichia coli and Staphylococcus thermophilus. -!- Belongs to peptidase families M17 and M28.

UniProtKB Entries (1)

Vibrio proteolyticus
Bacterial leucyl aminopeptidase

PDB Structure

PDB 3B35
External Links
Organism Escherichia
Primary Citation
Zinc coordination geometry and ligand binding affinity: the structural and kinetic analysis of the second-shell serine 228 residue and the methionine 180 residue of the aminopeptidase from Vibrio proteolyticus.
Ataie, N.J., Hoang, Q.Q., Zahniser, M.P., Tu, Y., Milne, A., Petsko, G.A., Ringe, D.