CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.1350.10
Functional Family tRNA-splicing endonuclease

Enzyme Information

4.6.1.16
tRNA-intron lyase.
based on mapping to UniProt Q9YBF1
PretRNA = a 3'-half-tRNA molecule with a 5'-OH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end + an intron with a 2',3'-cyclic phosphate and a 5'-hydroxyl terminus.
-!- The enzyme catalyzes the final stage in the maturation of tRNA molecules. -!- Formerly EC 3.1.27.9.

UniProtKB Entries (1)

Q9YBF1
ENDA_AERPE
Aeropyrum pernix K1
TRNA-splicing endonuclease

PDB Structure

PDB 3AJV
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A Conserved Lysine Residue in the Crenarchaea-Specific Loop is Important for the Crenarchaeal Splicing Endonuclease Activity.
Okuda, M., Shiba, T., Inaoka, D.K., Kita, K., Kurisu, G., Mineki, S., Harada, S., Watanabe, Y., Yoshinari, S.
J.Mol.Biol.