CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.47.10
Functional Family Chalcone synthase 1

Enzyme Information

2.3.1.212
Benzalacetone synthase.
based on mapping to UniProt Q94FV7
4-coumaroyl-CoA + malonyl-CoA + H(2)O = 2 CoA + 4-hydroxybenzalacetone + 2 CO(2).
-!- A polyketide synthase that catalyzes the C(6)-C(4) skeleton of phenylbutanoids in higher plants.

UniProtKB Entries (1)

Q94FV7
BAS_RHEPA
Rheum palmatum
Polyketide synthase BAS

PDB Structure

PDB 3A5R
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A structure-based mechanism for benzalacetone synthase from Rheum palmatum
Morita, H., Shimokawa, Y., Tanio, M., Kato, R., Noguchi, H., Sugio, S., Kohno, T., Abe, I.
Proc.Natl.Acad.Sci.USA