CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family MAP kinase-activated protein kinase 2

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P49137
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

P49137
MAPK2_HUMAN
Homo sapiens
MAP kinase-activated protein kinase 2

PDB Structure

PDB 3A2C
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural analysis of an MK2-inhibitor complex: insight into the regulation of the secondary structure of the Gly-rich loop by TEI-I01800
Fujino, A., Fukushima, K., Namiki, N., Kosugi, T., Takimoto-Kamimura, M.
Acta Crystallogr.,Sect.D