CATH Classification

Domain Context

CATH Clusters

Superfamily Fructose-1,6-Bisphosphatase, subunit A, domain 1
Functional Family Fructose-1,6-bisphosphatase 1

Enzyme Information

3.1.3.11
Fructose-bisphosphatase.
based on mapping to UniProt P09467
D-fructose 1,6-bisphosphate + H(2)O = D-fructose 6-phosphate + phosphate.
-!- The animal enzyme also acts on sedoheptulose 1,7-bisphosphate.

UniProtKB Entries (1)

P09467
F16P1_HUMAN
Homo sapiens
Fructose-1,6-bisphosphatase 1

PDB Structure

PDB 3A29
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Synthesis, SAR, and X-ray structure of tricyclic compounds as potent FBPase inhibitors
Tsukada, T., Takahashi, M., Takemoto, T., Kanno, O., Yamane, T., Kawamura, S., Nishi, T.
Bioorg.Med.Chem.Lett.