CATH Classification

Domain Context

CATH Clusters

Superfamily Aspartate Aminotransferase, domain 1
Functional Family

Enzyme Information

4.1.1.12
Aspartate 4-decarboxylase.
based on mapping to UniProt Q93QX0
L-aspartate = L-alanine + CO(2).
-!- Also catalyzes the decarboxylation of aminomalonate and the desulfination of 3-sulfino-L-alanine to sulfite and alanine. -!- Formerly EC 4.1.1.10.
2.6.1.1
Aspartate transaminase.
based on mapping to UniProt Q93QX0
L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.
-!- Also acts on L-tyrosine, L-phenylalanine and L-tryptophan. -!- This activity can be formed from EC 2.6.1.57 by controlled proteolysis.

UniProtKB Entries (1)

Q93QX0
ASDA_COMTE
Comamonas testosteroni
Bifunctional aspartate aminotransferase and L-aspartate beta-decarboxylase

PDB Structure

PDB 2ZY3
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure, Assembly, and Mechanism of a PLP-Dependent Dodecameric l-Aspartate beta-Decarboxylase
Chen, H.-J., Ko, T.-P., Lee, C.-Y., Wang, N.-C., Wang, A.H.-J.
Structure