CATH Classification

Domain Context

CATH Clusters

Superfamily Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
Functional Family

Enzyme Information

2.4.1.217
Mannosyl-3-phosphoglycerate synthase.
based on mapping to UniProt O58689
GDP-mannose + 3-phospho-D-glycerate = GDP + 2-(alpha-D-mannosyl)-3- phosphoglycerate.
-!- The enzyme is absolutely specific for GDP-mannose and 3-phosphoglycerate, and transfers the mannosyl group with retention of configuration. -!- In the hyperthermophilic archaeon Pyrococcus horikoshii, the mannosyl-3-phosphoglycerate formed is subsequently dephosphorylated by a specific phosphatase, EC 3.1.3.70, producing mannosylglycerate.

UniProtKB Entries (1)

O58689
MPGS_PYRHO
Pyrococcus horikoshii OT3
Mannosyl-3-phosphoglycerate synthase

PDB Structure

PDB 2ZU7
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of mannosyl-3-phosphoglycerate synthase from Pyrococcus horikoshii
Kawamura, T., Watanabe, N., Tanaka, I.
To be Published