CATH Classification

Domain Context

CATH Clusters

Superfamily DD-peptidase/beta-lactamase superfamily
Functional Family

Enzyme Information

3.5.2.6
Beta-lactamase.
based on mapping to UniProt Q47066
A beta-lactam + H(2)O = a substituted beta-amino acid.
-!- Zinc is only requires in class-B enzymes. -!- A group of enzymes of varying specificity hydrolyzing beta-lactams; some act more rapidly on penicillins, some more rapidly on cephalosporins. -!- Formerly EC 3.5.2.8.

UniProtKB Entries (1)

Q47066
BLT1_ECOLX
Escherichia coli
Beta-lactamase Toho-1

PDB Structure

PDB 2ZQA
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Basis of Extend Spectrum Beta-Lactamase in Correlation of Enzymatic Kinetics and Thermal Stability of Acyl-Intermediates
Nitanai, Y., Shimamura, T., Uchiyama, T., Ishii, Y., Takehira, M., Yutan, K., Matsuzawa, H., Miyano, M.
To be Published