CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.10140 | Toll/interleukin-1 receptor homology (TIR) domain |
Domain Context
CATH Clusters
| Superfamily | Toll/interleukin-1 receptor homology (TIR) domain |
| Functional Family | Myeloid differentiation primary response protein MyD88 |
Enzyme Information
UniProtKB Entries (1)
| Q99836 |
MYD88_HUMAN
Homo sapiens
Myeloid differentiation primary response protein MyD88
|
PDB Structure
| PDB | 2Z5V |
| External Links | |
| Method | SOLUTION NMR |
| Organism | |
| Primary Citation |
Structural basis for the multiple interactions of the MyD88 TIR domain in TLR4 signaling.
Proc.Natl.Acad.Sci.USA
|