CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.1280 | Alpha/beta knot |
|
3.40.1280.10 | SPOUT methyltransferase, trefoil knot domain |
Domain Context
CATH Clusters
| Superfamily | 3.40.1280.10 |
| Functional Family |
Enzyme Information
| 2.1.1.206 |
tRNA (cytidine(56)-2'-O)-methyltransferase.
based on mapping to UniProt O58214
S-adenosyl-L-methionine + cytidine(56) in tRNA = S-adenosyl-L- homocysteine + 2'-O-methylcytidine(56) in tRNA.
-!- The archaeal enzyme specifically catalyzes the S-adenosyl-L- methionine dependent 2'-O-ribose methylation of cytidine at position 56 in tRNA transcripts.
|
UniProtKB Entries (1)
| O58214 |
TRM56_PYRHO
Pyrococcus horikoshii OT3
TRNA (cytidine(56)-2'-O)-methyltransferase
|
PDB Structure
| PDB | 2YY8 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
Crystal structure and mutational study of a unique SpoU family archaeal methylase that forms 2'-O-methylcytidine at position 56 of tRNA
J.Mol.Biol.
|