CATH Classification

Domain Context

CATH Clusters

Superfamily SH2 domain
Functional Family Tyrosine-protein phosphatase non-receptor type

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt P29350
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

P29350
PTN6_HUMAN
Homo sapiens
Tyrosine-protein phosphatase non-receptor type 6

PDB Structure

PDB 2YU7
External Links
Method SOLUTION NMR
Organism
Primary Citation
Solution structure of the SHP-1 C-terminal SH2 domain complexed with a tyrosine-phosphorylated peptide from NKG2A
Kasai, T., Koshiba, S., Inoue, M., Kigawa, T., Yokoyama, S.
To be Published