CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.418 | Actin-binding Protein, T-fimbrin; domain 1 |
|
1.10.418.10 | Calponin-like domain |
Domain Context
CATH Clusters
| Superfamily | Calponin-like domain |
| Functional Family | Neuron navigator 2 |
Enzyme Information
| 3.6.4.12 |
DNA helicase.
based on mapping to UniProt Q8IVL1
ATP + H(2)O = ADP + phosphate.
-!- DNA helicases utilize the energy from ATP hydrolysis to unwind double-stranded DNA. -!- Some of them unwind duplex DNA with a 3' to 5' polarity (1,3,5,8), other show 5' to 3' polarity (10,11,12,13) or unwind DNA in both directions (14,15). -!- Some helicases unwind DNA as well as RNA (4,9). -!- May be identical with EC 3.6.4.13 (RNA helicase).
|
UniProtKB Entries (1)
| Q8IVL1 |
NAV2_HUMAN
Homo sapiens
Neuron navigator 2
|
PDB Structure
| PDB | 2YRN |
| External Links | |
| Method | SOLUTION NMR |
| Organism | |
| Primary Citation |
Solution structure of the CH domain from Human Neuron navigator 2
To be Published
|