CATH Classification

Domain Context

CATH Clusters

Superfamily Malonyl-CoA decarboxylase, oligemerization domain
Functional Family Malonyl-CoA decarboxylase, mitochondrial

Enzyme Information

4.1.1.9
Malonyl-CoA decarboxylase.
based on mapping to UniProt O95822
Malonyl-CoA = acetyl-CoA + CO(2).
-!- Specific for malonyl-CoA. -!- The enzyme from Pseudomonas ovalis also catalyzes the reaction of EC 2.8.3.3.

UniProtKB Entries (1)

O95822
DCMC_HUMAN
Homo sapiens
Malonyl-CoA decarboxylase, mitochondrial

PDB Structure

PDB 2YGW
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structures of Malonyl-Coenzyme a Decarboxylase Provide Insights Into its Catalytic Mechanism and Disease-Causing Mutations.
Froese, D.S., Forouhar, F., Tran, T.H., Vollmar, M., Kim, Y.S., Lew, S., Neely, H., Seetharaman, J., Shen, Y., Xiao, R., Acton, T.B., Everett, J.K., Cannone, G., Puranik, S., Savitsky, P., Krojer, T., Pilka, E.S., Kiyani, W., Lee, W.H., Marsden, B.D., von Delft, F., Allerston, C.K., Spagnolo, L., Gileadi, O., Montelione, G.T., Oppermann, U., Yue, W.W., Tong, L.
Structure