1 keywords

CATH Domain 2ybxA02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.810 Phosphatidylinositol Phosphate Kinase Iibeta; Chain: A, domain 2
Homologous Superfamily 3.30.810.10 2-Layer Sandwich

Domain Context

CATH Clusters

Superfamily 2-Layer Sandwich
Functional Family Phosphatidylinositol 5-phosphate 4-kinase type-2 beta

Enzyme Information

2.7.1.149
1-phosphatidylinositol-5-phosphate 4-kinase.
based on mapping to UniProt P48426
ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate = ADP + 1-phosphatidyl- 1D-myo-inositol 4,5-bisphosphate.

UniProtKB Entries (1)

P48426
PI42A_HUMAN
Homo sapiens
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

PDB Structure

PDB 2YBX
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of Human Phosphatidylinositol-5-Phosphate 4-Kinase Type-2 Alpha
Tresaugues, L., Moche, M., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Ekblad, T., Flodin, S., Graslund, S., Karlberg, T., Kotenyova, T., Kouznetsova, E., Nyman, T., Persson, C., Schuler, H., Siponen, M.I., Thorsell, A.G., Wahlberg, E., Weigelt, J., Nordlund, P.
To be Published