CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.450.40
Functional Family Oxygen sensor histidine kinase response regulator DevS/DosS

Enzyme Information

2.7.13.3
Histidine kinase.
based on mapping to UniProt P9WGK3
ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.
-!- This entry has been included to accommodate those protein-histidine kinases for which the phosphorylation site has not been established (i.e. either the pros- or tele-nitrogen of histidine). -!- A number of histones can act as acceptor.

UniProtKB Entries (1)

P9WGK3
DEVS_MYCTU
Mycobacterium tuberculosis H37Rv
Oxygen sensor histidine kinase response regulator DevS/DosS

PDB Structure

PDB 2Y8H
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Blockage of the Channel to Heme by the E87 Side Chain in the Gaf Domain of Mycobacterium Tuberculosis Doss Confers the Unique Sensitivity of Doss to Oxygen.
Cho, H.Y., Cho, H.J., Kim, M.H., Kang, B.S.
FEBS Lett.