CATH Domain 2y8cA01

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.70	Distorted Sandwich
	2.70.40	Deoxyuridine 5'-Triphosphate Nucleotidohydrolase; Chain A
	2.70.40.10	Deoxyuridine triphosphatase (dUTPase)

Domain Context

CATH Clusters

Superfamily	2.70.40.10
Functional Family	dUTP pyrophosphatase

Enzyme Information

UniProtKB Entries (1)

Q8II92_PLAF7

Plasmodium falciparum 3D7

Deoxyuridine 5'-triphosphate nucleotidohydrolase

PDB Structure

PDB	2Y8C
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Beta-Branched Acyclic Nucleoside Analogues as Inhibitors of Plasmodium Falciparum Dutpase Baragana, B., Mccarthy, O., Sanchez, P., Bosch, C., Kaiser, M., Brun, R., Whittingham, J.L., Roberts, S., Zhou, X.-X., Wilson, K.S., Johansson, N.G., Gonzalez-Pacanowska, D., Gilbert, I.H. Bioorg.Med.Chem.