CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.190.80
Functional Family Fructose-1,6-bisphosphatase class 1

Enzyme Information

3.1.3.11
Fructose-bisphosphatase.
based on mapping to UniProt P09467
D-fructose 1,6-bisphosphate + H(2)O = D-fructose 6-phosphate + phosphate.
-!- The animal enzyme also acts on sedoheptulose 1,7-bisphosphate.

UniProtKB Entries (1)

P09467
F16P1_HUMAN
Homo sapiens
Fructose-1,6-bisphosphatase 1

PDB Structure

PDB 2Y5K
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Orally Active Aminopyridines as Inhibitors of Tetrameric Fructose-1,6-Bisphosphatase.
Hebeisen, P., Haap, W., Kuhn, B., Mohr, P., Wessel, H.P., Zutter, U., Kirchner, S., Ruf, A., Benz, J., Joseph, C., Alvarez-Sanchez, R., Gubler, M., Schott, B., Benardeau, A., Tozzo, E., Kitas, E.
Bioorg.Med.Chem.Lett.