CATH Classification

Domain Context

CATH Clusters

Superfamily Peptidoglycan recognition protein-like
Functional Family 1,6-anhydro-N-acetylmuramyl-L-alanine amidase

Enzyme Information

3.5.1.28
N-acetylmuramoyl-L-alanine amidase.
based on mapping to UniProt P82974
Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.
-!- Formerly EC 3.4.12.5, EC 3.4.17.7 and EC 3.4.19.10.

UniProtKB Entries (1)

P82974
AMPD_CITFR
Citrobacter freundii
1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD

PDB Structure

PDB 2Y2B
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structures of Bacterial Peptidoglycan Amidase Ampd and an Unprecedented Activation Mechanism.
Carrasco-Lopez, C., Rojas-Altuve, A., Zhang, W., Hesek, D., Lee, M., Barbe, S., Andre, I., Ferrer, P., Silva-Martin, N., Castro, G.R., Martinez-Ripoll, M., Mobashery, S., Hermoso, J.A.
J.Biol.Chem.