CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleoside phosphorylase domain
Functional Family Uridine phosphorylase 2

Enzyme Information

2.4.2.3
Uridine phosphorylase.
based on mapping to UniProt O95045
Uridine + phosphate = uracil + alpha-D-ribose 1-phosphate.
-!- The enzyme participates the the pathways of pyrimidine ribonucleosides degradation and salvage. -!- The mammalian enzyme also accepts 2'-deoxyuridine. -!- Formerly EC 2.4.2.23.

UniProtKB Entries (1)

O95045
UPP2_HUMAN
Homo sapiens
Uridine phosphorylase 2

PDB Structure

PDB 2XRF
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of Human Uridine Phosphorylase 2
Welin, M., Moche, M., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, I., Karlberg, T., Kol, S., Kotenyova, T., Kouznetsova, E., Nyman, T., Persson, C., Schuler, H., Schutz, P., Siponen, M.I., Thorsell, A.G., Tresaugues, L., Van Der Berg, S., Wahlberg, E., Weigelt, J., Nordlund, P.
To be Published