CATH Classification

Domain Context

CATH Clusters

Superfamily Ribonuclease H-like superfamily/Ribonuclease H
Functional Family

Enzyme Information

2.7.7.7
DNA-directed DNA polymerase.
based on mapping to UniProt P56689
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.

UniProtKB Entries (1)

P56689
DPOL_THEGO
Thermococcus gorgonarius
DNA polymerase

PDB Structure

PDB 2XHB
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Probing the Interaction of Archaeal DNA Polymerases with Deaminated Bases Using X-Ray Crystallography and Non-Hydrogen Bonding Isosteric Base Analogues.
Killelea, T., Ghosh, S., Tan, S.S., Heslop, P., Firbank, S.J., Kool, E.T., Connolly, B.A.
Biochemistry