CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.2020 |
Domain Context
CATH Clusters
| Superfamily | 3.40.50.2020 |
| Functional Family | Xanthine phosphoribosyltransferase 1 |
Enzyme Information
| 2.4.2.8 |
Hypoxanthine phosphoribosyltransferase.
based on mapping to UniProt Q04178
IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate.
-!- Guanine and 6-mercaptopurine can replace hypoxanthine.
|
UniProtKB Entries (1)
| Q04178 |
HPRT_YEAST
Saccharomyces cerevisiae S288C
Hypoxanthine-guanine phosphoribosyltransferase
|
PDB Structure
| PDB | 2XBU |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Functional Significance of Four Successive Glycine Residues in the Pyrophosphate Binding Loop of Fungal 6-Oxopurine Phosphoribosyltransferases.
Protein Sci.
|