CATH Classification

Domain Context

CATH Clusters

Superfamily OMPT-like
Functional Family

Enzyme Information

3.4.23.48
Plasminogen activator Pla.
based on mapping to UniProt P17811
Converts human Glu-plasminogen to plasmin by cleaving the 560-Arg-|-Val- 561 peptide bond that is also hydrolyzed by the mammalian u-plasminogen activator and t-plasminogen activator. Also cleaves arginyl bonds in other proteins.
-!- From the bacterium Yersinia pestis that causes plague. -!- Belongs to peptidase family A26.

UniProtKB Entries (1)

P17811
COLY_YERPE
Yersinia pestis
Coagulase/fibrinolysin

PDB Structure

PDB 2X56
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
An Active Site Water Network in the Plasminogen Activator Pla from Yersinia Pestis
Eren, E., Murphy, M., Goguen, J., van den Berg, B.
Structure