CATH Classification

Domain Context

CATH Clusters

Superfamily HAD superfamily/HAD-like
Functional Family Phospholysine phosphohistidine inorganic pyrophosphate phosphatase

Enzyme Information

3.1.3.-
Phosphoric monoester hydrolases.
based on mapping to UniProt Q9H008
3.6.1.1
Inorganic diphosphatase.
based on mapping to UniProt Q9H008
Diphosphate + H(2)O = 2 phosphate.
-!- Specificity varies with the source and with the activating metal ion. -!- The enzyme from some sources may be identical with EC 3.1.3.1 or EC 3.1.3.9. -!- Cf. EC 7.1.3.1.

UniProtKB Entries (1)

Q9H008
LHPP_HUMAN
Homo sapiens
Phospholysine phosphohistidine inorganic pyrophosphate phosphatase

PDB Structure

PDB 2X4D
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of Human Phospholysine Phosphohistidine Inorganic Pyrophosphate Phosphatase Lhpp
Vollmar, M., Gileadi, C., Guo, K., Savitsky, P., Muniz, J.R.C., Yue, W., Allerston, C., von Delft, F., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., Kavanagh, K.L., Oppermann, U.
To be Published