CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family Coagulation factor X

Enzyme Information

3.4.21.22
Coagulation factor IXa.
based on mapping to UniProt P00740
Selective cleavage of Arg-|-Ile bond in factor X to form factor Xa.
-!- The proenzyme factor IX is activated by EC 3.4.21.27. -!- Belongs to peptidase family S1.

UniProtKB Entries (1)

P00740
FA9_HUMAN
Homo sapiens
Coagulation factor IX

PDB Structure

PDB 2WPL
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Basis of the Cofactor- and Substrate-Assisted Activation of Human Coagulation Factor Ixa
Zogg, T., Brandstetter, H.
Structure