CATH Classification

Domain Context

CATH Clusters

Superfamily FAD/NAD(P)-binding domain
Functional Family Trypanothione reductase

Enzyme Information

UniProtKB Entries (1)

Q389T8
Q389T8_TRYB2
Trypanosoma brucei brucei TREU927
Trypanothione reductase

PDB Structure

PDB 2WP6
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Dihydroquinazolines as a Novel Class of Trypanosoma Brucei Trypanothione Reductase Inhibitors: Discovery, Synthesis, and Characterization of Their Binding Mode by Protein Crystallography.
Patterson, S., Alphey, M.S., Jones, D.C., Shanks, E.J., Street, I.P., Frearson, J.A., Wyatt, P.G., Gilbert, I.H., Fairlamb, A.H.
J.Med.Chem.