1 keywords

CATH Domain 2wefA01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.540 Fructose-1,6-Bisphosphatase; Chain A, domain 1
Homologous Superfamily 3.30.540.10 Fructose-1,6-Bisphosphatase, subunit A, domain 1

Domain Context

CATH Clusters

Superfamily Fructose-1,6-Bisphosphatase, subunit A, domain 1
Functional Family Bisphosphate nucleotidase 1

Enzyme Information

3.1.3.7
3'(2'),5'-bisphosphate nucleotidase.
based on mapping to UniProt O95861
Adenosine 3',5'-bisphosphate + H(2)O = adenosine 5'-phosphate + phosphate.
-!- Also acts on 3'-phosphoadenylylsulfate, and on the corresponding 2'-phosphates.

UniProtKB Entries (1)

O95861
BPNT1_HUMAN
Homo sapiens
3'(2'),5'-bisphosphate nucleotidase 1

PDB Structure

PDB 2WEF
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Human 3'(2'), 5'-Bisphosphate Nucleotidase 1 (Bpnt1) in Complex with AMP, Po4 and Magnesium
Moche, M., Schutz, P., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotenyova, T., Nilsson, M.E., Nyman, T., Persson, C., Sagemark, J., Schueler, H., Siponen, M.I., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Welin, M., Wisniewska, M., Nordlund, P.
To be Published