CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.1350.10
Functional Family

Enzyme Information

3.1.22.4
Crossover junction endodeoxyribonuclease.
based on mapping to UniProt O28314
Endonucleolytic cleavage at a junction such as a reciprocal single- stranded crossover between two homologous DNA duplexes (Holliday junction).
-!- The enzyme from Saccharomyces cerevisiae has no endonuclease or exonuclease activity on single-stranded or double-stranded DNA molecules that do not contain Holliday junctions.

UniProtKB Entries (1)

O28314
HJC_ARCFU
Archaeoglobus fulgidus DSM 4304
Holliday junction resolvase Hjc

PDB Structure

PDB 2WCW
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
1.6 A Resolution Structure of Archaeoglobus Fulgidus Hjc, a Holliday Junction Resolvase from an Archaeal Hyperthermophile
Carolis, C., Koehler, C., Sauter, C., Basquin, J., Suck, D., Toeroe, I.
To be Published