CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family ATP-dependent RNA helicase DDX6

Enzyme Information

3.6.4.13
RNA helicase.
based on mapping to UniProt P26196
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).

UniProtKB Entries (1)

Q96F86
EDC3_HUMAN
Homo sapiens
Enhancer of mRNA-decapping protein 3

PDB Structure

PDB 2WAY
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Basis for the Mutually Exclusive Anchoring of P Body Components Edc3 and Tral to the Dead Box Protein Ddx6/Me31B.
Tritschler, F., Braun, J.E., Eulalio, A., Truffault, V., Izaurralde, E., Weichenrieder, O.
Mol.Cell