1 keywords

CATH Domain 2w4lA00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.140 Cytidine Deaminase; domain 2
Homologous Superfamily 3.40.140.10 Cytidine Deaminase, domain 2

Domain Context

CATH Clusters

Superfamily Cytidine Deaminase, domain 2
Functional Family Deoxycytidylate deaminase

Enzyme Information

3.5.4.12
dCMP deaminase.
based on mapping to UniProt P32321
dCMP + H(2)O = dUMP + NH(3).
-!- Also acts on some 5-substituted dCMPs.

UniProtKB Entries (1)

P32321
DCTD_HUMAN
Homo sapiens
Deoxycytidylate deaminase

PDB Structure

PDB 2W4L
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Crystal Structure of Human Dcmp Deaminase
Siponen, M.I., Moche, M., Arrowsmith, C.H., Berglund, H., Bountra, C., Collins, R., Dahlgren, L.G., Edwards, A.M., Flodin, S., Flores, A., Graslund, S., Hammarstrom, M., Johansson, A., Johansson, I., Karlberg, T., Kotenyova, T., Lehtio, L., Nilsson, M.E., Nyman, T., Persson, C., Sagemark, J., Schuler, H., Thorsell, A.G., Tresaugues, L., Van Den Berg, S., Weigelt, J., Welin, M., Wikstrom, M., Wisniewska, M., Nordlund, P.
To be Published