CATH Classification

Domain Context

CATH Clusters

Superfamily arginine biosynthesis bifunctional protein suprefamily
Functional Family

Enzyme Information

2.3.1.35
Glutamate N-acetyltransferase.
based on mapping to UniProt P0DJQ5
N(2)-acetyl-L-ornithine + L-glutamate = L-ornithine + N-acetyl-L- glutamate.
-!- Also has some hydrolytic activity on acetyl-L-ornithine, but the rate is 1% of that of transferase activity.
2.3.1.1
Amino-acid N-acetyltransferase.
based on mapping to UniProt P0DJQ5
Acetyl-CoA + L-glutamate = CoA + N-acetyl-L-glutamate.
-!- Also acts with L-aspartate and, more slowly, with some other amino acids.

UniProtKB Entries (1)

P0DJQ5
GNAT2_STRCL
Streptomyces clavuligerus
Glutamate N-acetyltransferase 2

PDB Structure

PDB 2VZK
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Anatomy of a Simple Acyl Intermediate in Enzyme Catalysis: Combined Biophysical and Modeling Studies on Ornithine Acetyl Transferase.
Iqbal, A., Clifton, I.J., Bagonis, M., Kershaw, N.J., Domene, C., Claridge, T.D., Wharton, C.W., Schofield, C.J.
J.Am.Chem.Soc.