CATH Classification

Domain Context

CATH Clusters

Superfamily 2.60.120.200
Functional Family Botulinum neurotoxin type A

Enzyme Information

3.4.24.69
Bontoxilysin.
based on mapping to UniProt Q60393
Limited hydrolysis of proteins of the neuroexocytosis apparatus, synaptobrevins, SNAP25 or syntaxin. No detected action on small molecule substrates.
-!- Belongs to peptidase family M27.

UniProtKB Entries (1)

Q60393
BXG_CLOBO
Clostridium botulinum
Botulinum neurotoxin type G

PDB Structure

PDB 2VXR
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of the Botulinum Neurotoxin Type G Binding Domain: Insight Into Cell Surface Binding.
Stenmark, P., Dong, M., Dupuy, J., Chapman, E.R., Stevens, R.C.
J.Mol.Biol.