1 keywords

CATH Domain 2vvxA00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.437 Apoptosis Regulator Bcl-x
Homologous Superfamily 1.10.437.20 dsDNA poxvirus

Domain Context

CATH Clusters

Superfamily dsDNA poxvirus
Functional Family

Enzyme Information

UniProtKB Entries (1)

Q01220
A52_VACCW
Vaccinia virus WR
Protein A52

PDB Structure

PDB 2VVX
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Vaccinia Virus Proteins A52 and B14 Share a Bcl-2-Like Fold But Have Evolved to Inhibit NF-kappaB Rather Than Apoptosis
Graham, S.C., Bahar, M.W., Cooray, S., Chen, R.A.-J., Whalen, D.M., Abrescia, N.G.A., Alderton, D., Owens, R.J., Stuart, D.I., Smith, G.L., Grimes, J.M.
Plos Pathog.