CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family serine/threonine-protein kinase haspin

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q8TF76
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

Q8TF76
HASP_HUMAN
Homo sapiens
Serine/threonine-protein kinase haspin

PDB Structure

PDB 2VUW
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure and Functional Characterization of the Atypical Human Kinase Haspin.
Eswaran, J., Patnaik, D., Filippakopoulos, P., Wang, F., Stein, R.L., Murray, J.W., Higgins, J.M.G., Knapp, S.
Proc.Natl.Acad.Sci.USA