CATH Classification

Domain Context

CATH Clusters

Superfamily 2.30.42.10
Functional Family Tyrosine-protein phosphatase non-receptor type

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt P29074
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

P29074
PTN4_HUMAN
Homo sapiens
Tyrosine-protein phosphatase non-receptor type 4

PDB Structure

PDB 2VPH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of the Human Protein Tyrosine Phosphatase, Non-Receptor Type 4, Pdz Domain
Roos, A.K., Wang, J., Burgess-Brown, N., Elkins, J.M., Kavanagh, K., Pike, A.C.W., Filippakopoulos, P., Arrowsmith, C.H., Weigelt, J., Edwards, A., von Delft, F., Bountra, C., Knapp, S.
To be Published