CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.970 | Thiamin diphosphate (ThDP)-binding fold, Pyr/PP domains |
Domain Context
CATH Clusters
| Superfamily | 3.40.50.970 |
| Functional Family | Pyruvate decarboxylase isozyme |
Enzyme Information
| 4.1.1.1 |
Pyruvate decarboxylase.
based on mapping to UniProt Q12629
A 2-oxo acid = an aldehyde + CO(2).
-!- Also catalyzes acyloin formation.
|
UniProtKB Entries (1)
| Q12629 |
PDC1_KLULA
Kluyveromyces lactis NRRL Y-1140
Pyruvate decarboxylase
|
PDB Structure
| PDB | 2VK4 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Allosteric Activation of Pyruvate Decarboxylases. A Never-Ending Story.
J.Mol.Catal., B Enzym.
|
