CATH Classification

Domain Context

CATH Clusters

Superfamily Vaccinia Virus protein VP39
Functional Family tRNA (guanine-N(7)-)-methyltransferase

Enzyme Information

2.1.1.33
tRNA (guanine(46)-N(7))-methyltransferase.
based on mapping to UniProt Q12009
S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.
-!- The enzyme specifically methylates guanine(46) at N(7) in tRNA.

UniProtKB Entries (1)

Q12009
TRMB_YEAST
Saccharomyces cerevisiae S288C
TRNA (guanine-N(7)-)-methyltransferase

PDB Structure

PDB 2VDV
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of the Yeast tRNA M7G Methylation Complex.
Leulliot, N., Chaillet, M., Durand, D., Ulryck, N., Blondeau, K., Van Tilbeurgh, H.
Structure