CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family Rho-associated protein kinase 1

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q13464
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

P61587
RND3_HUMAN
Homo sapiens
Rho-related GTP-binding protein RhoE

PDB Structure

PDB 2V55
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Mechanism of Multi-Site Phosphorylation from a Rock-I:Rhoe Complex Structure.
Komander, D., Garg, R., Wan, P.T.C., Ridley, A.J., Barford, D.
Embo J.