CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family Chymotrypsin-like elastase family member 1

Enzyme Information

3.4.21.36
Pancreatic elastase.
based on mapping to UniProt P00772
Hydrolysis of proteins, including elastin. Preferential cleavage: Ala-|-Xaa.
-!- Formed by activation of proelastase from mammalian pancreas by trypsin. -!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.7 and EC 3.4.21.11.

UniProtKB Entries (1)

P00772
CELA1_PIG
Sus scrofa
Chymotrypsin-like elastase family member 1

PDB Structure

PDB 2V35
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Efficiency of C-4 Substituents in Activating the Beta-Lactam Scaffold Towards Serine Proteases and Hydroxide Ion.
Mulchande, J., Martins, L., Moreira, R., Archer, M., Oliveira, T.F., Iley, J.
Org.Biomol.Chem.