CATH Classification

Domain Context

CATH Clusters

Superfamily FAD-linked oxidase, cap domain/gating helix
Functional Family

Enzyme Information

2.5.1.26
Alkylglycerone-phosphate synthase.
based on mapping to UniProt O96759
1-acyl-glycerone 3-phosphate + a long-chain alcohol = an alkyl-glycerone 3-phosphate + a long-chain acid anion.
-!- The ester-linked fatty acid of the substrate is cleaved and replaced by a long-chain alcohol in an ether linkage.

UniProtKB Entries (1)

O96759
ADAS_DICDI
Dictyostelium discoideum
Alkyldihydroxyacetonephosphate synthase

PDB Structure

PDB 2UUU
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Crucial Step in Ether Phospholipid Biosynthesis: Structural Basis of a Noncanonical Reaction Associated with a Peroxisomal Disorder.
Razeto, A., Mattiroli, F., Carpanelli, E., Aliverti, A., Pandini, V., Coda, A., Mattevi, A.
Structure