1 keywords

CATH Domain 2rkfA00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.40 Beta Barrel
Topology 2.40.70 Cathepsin D, subunit A; domain 1
Homologous Superfamily 2.40.70.10 Acid Proteases

Domain Context

CATH Clusters

Superfamily Acid Proteases
Functional Family Gag-Pol polyprotein

Enzyme Information

UniProtKB Entries (1)

A0F7J4
A0F7J4_9HIV1
Human immunodeficiency virus 1
Pol protein

PDB Structure

PDB 2RKF
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Ninety-nine is not enough: molecular characterization of inhibitor-resistant human immunodeficiency virus type 1 protease mutants with insertions in the flap region
Kozisek, M., Saskova, K.G., Rezacova, P., Brynda, J., van Maarseveen, N.M., De Jong, D., Boucher, C.A., Kagan, R.M., Nijhuis, M., Konvalinka, J.
J.Virol.