CATH Classification

Domain Context

CATH Clusters

Superfamily Penicillin V Acylase; Chain A
Functional Family

Enzyme Information

3.5.1.24
Choloylglycine hydrolase.
based on mapping to UniProt P54965
3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholan-24-oylglycine + H(2)O = 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholanate + glycine.
-!- Also acts on the 3-alpha,12-alpha-dihydroxy-derivative, and on choloyl-taurine.

UniProtKB Entries (1)

P54965
CBH_CLOPE
Clostridium perfringens str. 13
Choloylglycine hydrolase

PDB Structure

PDB 2RF8
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis for the catalytic activity and processing of the conjugated bile salt hydrolase from Clostridium perfringens
Rossmann, M., Saenger, W.
To be Published