CATH Classification

Domain Context

CATH Clusters

Superfamily 1.10.1740.80
Functional Family

Enzyme Information

2.7.7.48
RNA-directed RNA polymerase.
based on mapping to UniProt Q9Q6Q5
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
-!- Catalyzes RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. -!- Can initiate a chain de novo. -!- See also EC 2.7.7.6.

UniProtKB Entries (1)

Q9Q6Q5
RDRP_IBDV
Infectious bursal disease virus
RNA-directed RNA polymerase

PDB Structure

PDB 2R72
External Links
Method X-RAY DIFFRACTION
Organism Trichoplusia
Primary Citation
Activation mechanism of a noncanonical RNA-dependent RNA polymerase.
Garriga, D., Navarro, A., Querol-Audi, J., Abaitua, F., Rodriguez, J.F., Verdaguer, N.
Proc.Natl.Acad.Sci.Usa