CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.10 | Roll |
|
3.10.270 | Urate Oxidase |
|
3.10.270.10 | Urate Oxidase; |
Domain Context
CATH Clusters
| Superfamily | Urate Oxidase; |
| Functional Family |
Enzyme Information
| 3.5.4.16 |
GTP cyclohydrolase I.
based on mapping to UniProt Q82VD1
GTP + H(2)O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3- trihydroxypropyl)-dihydropteridine triphosphate.
-!- The reaction involves hydrolysis of two C-N bonds and isomerization of the pentose unit; the recyclization may be non-enzymic. -!- Involved in the de novo synthesis of tetrahydrobiopterin from GTP, with the other enzymes involved being EC 1.1.1.153 and EC 4.2.3.12.
|
UniProtKB Entries (1)
| Q82VD1 |
GCH4_NITEU
Nitrosomonas europaea ATCC 19718
GTP cyclohydrolase FolE2
|
PDB Structure
| PDB | 2R5R |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | Escherichia |
| Primary Citation |
The crystal structure of DUF198 from Nitrosomonas europaea ATCC 19718.
To be Published
|
