CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family

Enzyme Information

1.1.1.318
Eugenol synthase.
based on mapping to UniProt Q15GI4
Eugenol + a carboxylate + NADP(+) = a coniferyl ester + NADPH.
-!- The enzyme acts in the opposite direction. -!- The enzymes from the plants Ocimum basilicum (sweet basil), Clarkia breweri and Petunia hybrida only accept coniferyl acetate and form eugenol. -!- The enzyme from Pimpinella anisum (anise) forms anol (from 4-coumaryl acetate) in vivo, although the recombinant enzyme can form eugenol from coniferyl acetate. -!- The enzyme from Larrea tridentata (creosote bush) also forms chavicol from a coumaryl ester and can use NADH.

UniProtKB Entries (1)

Q15GI4
EGS1_OCIBA
Ocimum basilicum
Eugenol synthase 1

PDB Structure

PDB 2QX7
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structure and reaction mechanism of basil eugenol synthase
Louie, G.V., Baiga, T.J., Bowman, M.E., Koeduka, T., Taylor, J.H., Spassova, S.M., Pichersky, E., Noel, J.P.
Plos One