CATH Classification

Domain Context

CATH Clusters

Superfamily DnaJ domain
Functional Family putative tyrosine-protein phosphatase auxilin isoform X2

Enzyme Information

3.1.3.48
Protein-tyrosine-phosphatase.
based on mapping to UniProt Q27974
Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
-!- Dephosphorylates O-phosphotyrosine groups in phosphoproteins, such as the products of EC 2.7.10.2.

UniProtKB Entries (1)

Q27974
AUXI_BOVIN
Bos taurus
Putative tyrosine-protein phosphatase auxilin

PDB Structure

PDB 2QWN
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Structural basis of J cochaperone binding and regulation of Hsp70.
Jiang, J., Maes, E.G., Taylor, A.B., Wang, L., Hinck, A.P., Lafer, E.M., Sousa, R.
Mol.Cell